High Blood Protein (Hyperproteinemia): Levels, Causes & Treatment (2024)

What does it mean to have high protein in my blood?

Like its name, high protein in blood (hyperproteinemia) means the levels of protein in your blood plasma are higher than normal. Plasma is the liquid part of your blood. There are two main blood proteins — albumin and globulins:

  • Albumin: Your liver makes albumin protein. This protein keeps fluid from leaking from your blood vessels. It also helps enzymes, vitamins and other substances circulate throughout your body. A normal albumin range in an adult is 3.5 to 5.0 grams per deciliter (g/dl).
  • Globulins: Your liver and your immune system make globulins. This protein helps fight off infections. A normal globulin range in an adult is about 2.0 to 3.5 g/dl.

What are high blood protein symptoms?

High blood protein levels don’t cause symptoms. You may learn you have high blood protein if a healthcare provider orders a comprehensive metabolic panel. The results will show your total protein levels, albumin levels and the ratio of albumin to globulins, or A/G ratio. (A normal A/G ratio is 0.8 to 2.0.) If your blood protein levels are unusually high, a healthcare provider may order more tests, such as protein electrophoresis or total immunoglobulin levels.

Should I be worried if I have high blood protein?

No, you shouldn’t worry about a test result that shows your blood protein is higher than normal. Your test result doesn’t necessarily mean you have a serious illness. If your blood protein level is unusually high, your healthcare provider may order additional blood tests to get more information. They’ll also explain what may be causing a high blood protein level and what other tests they’ll order to identify the underlying condition.

High Blood Protein (Hyperproteinemia): Levels, Causes & Treatment (2024)
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