Second Trimester Abortion Procedure (2024)

During the second trimester, from 14 to 23 weeks and 6 days after your last menstrual period, abortions are typically performed over a two to three day period but don't require an overnight stay in the hospital. This procedure is known as a dilation and evacuation (D&E).

On the first day, you'll meet your medical team at the UCLA West Med Clinic to prepare for the procedure. This first visit typically takes about 3-4 hours.

On the day of the procedure, usually a Wednesday or a Friday, you'll meet the medical team at UCLA Ronald Reagan Medical Center. This visit will take about 6-8 hours.

Pre-Operative Appointment

In a private exam room, you will learn about your procedure, undergo an exam and ultrasound, and may receive oral pain/anxiety medications. You will receive prescriptions for pain medications and antibiotics. It is important that you follow the instructions provided by your doctor. You will have the option to discuss and choose a birth control method. You will also have the option to make arrangements for private cremation services if you choose.

Depending on your gestational age and medical history, cervical softening and dilating is performed with medication and/or small dilating sticks, called laminaria or Dilapan. Laminaria are thin sticks made from a special seaweed material that widen as they absorb moisture from your body. Dilapan are synthetic sticks that work in the same way. The dilators will stay in your cervix overnight, and allow the process of cervical dilation to happen slowly, which helps to prepare your body for the surgical procedure. Depending on your gestational age, you may come back for a second day of pre-op, during which the previous dilators will be removed and new ones will be put in. You may also receive an injection in the uterus that induces fetal demise.

During the dilator insertion, you'll be awake. The doctor will:

  • Give you pain and/or anxiety medication to help with discomfort
  • Place a speculum to view inside your vagin*.
  • Clean the cervix with gauze soaked in soap.
  • Apply numbing medication (local anesthesia) to the cervix.
  • Insert laminaria (or Dilapan) into your cervix, the opening to the uterus. The laminaria insertion takes about five to 10 minutes.

After the procedure, you will rest for a few minutes. You may experience cramping and spotting. You may get dressed when you feel able. Our nurse will give you detailed instructions on how to take care of your body overnight and how to prepare for the next day's procedure. She will also draw your blood as necessary.

Someone must drive you home if you take anti-anxiety or opiate pain medications. If needed, you and a support person can ride home together in an Uber/Lyft. Note: your driver/support person does NOT need to know you are having an abortion. They just need to be someone you can trust to get you home safely afterwards. We will not disclose your health information to anyone without your explicit consent. Rest at home until the medications wear off. It is recommended that you continue to relax at home for the rest of the day after your pre-op visit.

Surgical Appointment

Don't eat or drink after midnight on the day of your surgical procedure.

On the surgical day, you'll check-in at the hospital reception area at UCLA Ronald Reagan Medical Center then go to the pre-operative area, where you'll meet your medical team. They will begin to get you ready for the procedure.

Once you are in the procedure room, medication will be administered intravenously (IV) in your arm to induce anesthesia or loss of consciousness. Most patients fall asleep and don't remember the procedure. After you're well relaxed, the doctor will remove the laminaria and use gentle suction and gynecological instruments to empty your uterus, with ultrasound guidance. If you desired a contraceptive implant or intrauterine device, it will be placed in the operating room after your procedure. You'll be in the operating room for about an hour but the procedure will likely only take about 15 to 30 minutes.

Recovery

In the recovery room, nurses will monitor you for about two hours. You may have some cramping and spotting. The procedure and recovery period at the hospital usually takes about six to eight hours in total. Because of medications administered, you shouldn't drive until the medications wear off. Please make arrangements ahead of time for someone to take you home directly.You can expect to return to normal activities, such as work and school, the next day.

If you don't have anyone to accompany you home, contact ACCESS Reproductive Justice, a reproductive rights organization that may have a pro-choice volunteer driver to assist you. This must be coordinated with our clinic before your appointment, so please make arrangements as soon as possible. ACCESS can be reached via phone call or text message at 800-376-4636. Their usual hours are Monday-Friday, 10:00 am to 4:00 pm PST.

Follow-Up Visits

You will have a follow up appointment one to two weeks after your procedure to confirm that your procedure is completed and that you are healing well. This visit is typically done via telehealth, though you can also be seen for an in-person evaluation. At this visit, you can also get a prescription for birth control.

Safety and Effectiveness

Second trimester surgical abortion is one of the safest medical procedures. Although rare, possible complications include a blood clot in the uterus that can cause pain or require a repeat suction procedure; infection, which is generally easily identified and treated; a tear in the cervix that can be easily repaired with suture; perforation of the uterus; retained pregnancy tissue requiring a repeat suction procedure; and excessive bleeding requiring a transfusion. Complications from a surgical abortion are considerably rarer and much less serious than those associated with giving birth.

Second Trimester Abortion Procedure (2024)

FAQs

What is the failure rate of misoprostol in second trimester? ›

Termination of pregnancy in the second trimester using misoprostol has been shown to be safe and effective, with a success rate up to 90% in some of the published series [6,8-11]; however, the ideal regimen of misoprostol still remains to be determined, with more than thirty different dosage regimens described in the ...

What are the current and potential methods for second trimester abortion? ›

Similar to first-trimester abortion, second-trimester procedures can be performed surgically, with dilation and evacuation (D&E), or with induction (medication).

What is the time gap between mifepristone and misoprostol in the second trimester? ›

The most effective regimen for medication management of early pregnancy loss is 200 mg of oral mifepristone followed by 800 mcg of misoprostol administered vagin*lly 24 to 48 hours later. Regimens with misoprostol alone can be used if mifepristone is not available; however, rates of effectiveness are lower.

How long does it take for misoprostol to soften the cervix? ›

Wait for the pills to dissolve. After 30 minutes, swallow what is left of the pills. possible into the vagin*. Misoprostol causes the cervix to soften further and the uterus (womb) to contract, expelling the pregnancy, usually within the 4 – 6 hours after the misoprostol is taken.

Is misoprostol used for second trimester loss? ›

Misoprostol use in the context of second trimester fetal loss is more widely acceptable in maternal conditions than otherwise viable pregnancies. Patients with a history of one cesarean delivery may be safely induced with misoprostol with 0.28% risk of uterine rupture.

How much misoprostol is needed for the second trimester? ›

Recommended regimen for 13-24 weeks gestation:

Misoprostol 400mcg buccally, sublingually or vagin*lly every three hours until fetal and placental expulsion. vagin*l dosing is more effective than other routes.

What is the procedure for miscarriage in the second trimester? ›

Surgical evacuation: This procedure, called a dilation and evacuation, can be performed in the second trimester, typically up to about 24 weeks. Surgical evacuation is the most common treatment women choose and involves removing the pregnancy through the cervix in the operating room while you are asleep.

What is an inevitable abortion in the second trimester? ›

Cervical incompetence is the painless dilation of the cervix during the second trimester that leads to spontaneous rupture of membranes and subsequent expulsion of uterine contents.

What is the most common cause of second trimester recurrent abortion? ›

Genetic: Aneuploidy is one of the most common causes of RPL. Balanced, reciprocal, and Robertsonian translocations in the fetus can predispose to spontaneous miscarriages. Anatomic: Congenital Mullerian tract anomalies can cause RPL.

Is misoprostol alone for second trimester? ›

Where mifepristone is not available or affordable, misoprostol alone has also been shown to be effective, although a higher total dose is needed and efficacy is lower than for the combined regimen. Therefore, whenever possible, the combined regimen should be used.

What does mifepristone do in second trimester? ›

Mifepristone is anti-progesterone, which sensitises the myometrium to prostaglandins, increases uterine contractility, and softens and dilates the cervix. It is not sufficient for medical termination of pregnancy when used on its own but is effective when used synergistically with prostaglandins.

What is the success rate of misoprostol in 24 hours? ›

Simultaneous dosing of mifepristone and misoprostol for those with gestations up to 63 days has demonstrated a success rate of approximately 95%, compared to 97-98% when misoprostol is used 24-48 hours after mifepristone (Creinin et al., 2007; Goel et al., 2011; Lohr et al., 2018; Schmidt-Hansen et al., 2022; Verma et ...

Is misoprostol more effective, orally or inserted? ›

The recommended dose of misoprostol is 800 mcgs (4 200-mcg tablets) inserted vagin*lly. Study results have demonstrated that vagin*l administration is more effective than oral use of misoprostol. One dose is about 70% effective, and 2 is about 84% effective.

Does ripening of the cervix hurt? ›

It is also not uncommon to use different techniques to ripen the cervix. You may feel contractions during this process. If the contractions become painful, you will be able to request medication to relieve your discomfort. You will be advised as to what time to come to the hospital for your induction.

How long does it take to pass tissue with misoprostol? ›

Progesterone is a critical hormone for supporting an early pregnancy. The second medication, misoprostol, causes contractions and expels the pregnancy tissue. It typically takes 12 to 24 hours to pass the tissue.

What is the risk of miscarriage second trimester? ›

About 2-3% of pregnancies will be lost in the second trimester, a rate that is much lower than in the first trimester. Once a pregnancy gets to about 20 weeks gestation, less than 0.5% will end in a fetal demise. A loss at this time in pregnancy is most often a hard and sad experience.

What causes most 2nd trimester miscarriages? ›

Several long-term (chronic) health conditions can increase your risk of having a miscarriage in the second trimester, especially if they're not treated or well controlled. These include: diabetes (if it's poorly controlled) severe high blood pressure.

When is misoprostol less effective? ›

At 8 weeks pregnant or less, it works about 94-98% of the time. At 8-9 weeks pregnant, it works about 94-96% of the time. At 9-10 weeks pregnant, it works about 91-93% of the time. If you take an extra dose of misoprostol, it works about 99% of the time.

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