What Are The Strongest Psychoactive Cannabinoids? (2024)

FAQs

What Are The Strongest Psychoactive Cannabinoids? ›

THC-P. This brings us to the last and most potent psychoactive cannabinoid on the market. THC-P is derived from the hemp plant and also extracted similarly to Delta-8 THC, but it's wildly potent. THC-P is 30x stronger than Delta-9 THC, but some research indicates that it's actually 33x stronger.

The main difference between the two cannabinoids is that THC has strong psychoactive effects, meaning it makes a person 'high', whereas CBD is thought to have an anti-psychoactive effect that controls or moderates the 'high' caused by the THC.

The strongest type of THC is THCP (tetrahydrocannabiphorol). This cannabinoid is said to be 3 to 33 times as strong as regular delta-9 THC.

THCP and HHC have similar structures and produce similar effects and characteristic as conventional marijuana. The main difference is that THCP is much stronger than HHC and is much more intoxicating. Both compounds can be made from Delta-9 Tetrahydrocannabinol and Delta-8 Tetrahydrocannabinol.

Leafly reviewers say indica hybrids like Wedding Cake are the most arousing. For low-tolerance consumers, a balanced CBD:THC strain like CBD OG, or The Gift can reduce anxiety while stimulating the senses.

TAKEAWAYS: THC-O and delta-9 both provide a potent high, however, most people find that THC-O is roughly three to four times stronger than delta-9. Like delta-9, THC-O provides the signature euphoric high effects. Unlike delta-9, THC-O may induce psychedelic effects.

CBD isolate is the purest form of CBD. It may be a suitable product for first-time CBD users who wish to experiment with the potential health benefits, without the interference of other cannabis compounds, which may alter the effects. CBD isolate is also refined, so it has no discernible taste or odor.

The major active principle in all cannabis products is Δ⁹- tetrahydrocannabinol (Δ⁹-THC or simply THC), also known by its International Non-Proprietary Name (INN) as dronabinol.

It is a complex plant with about 426 chemical entities, of which more than 60 are cannabinoid compounds [Dewey, 1986]. The four major compounds are d-9-THC, CBD, d-8-THC and cannabinol, which have been most researched [Pertwee, 1997, 2008; Pamplona and Takahashi, 2012].

What's stronger, THCa or THCP? ›

Which is Stronger: THCA vs THCP? In a side-by-side comparison between THC-A vs. THC-P, THC-P comes out as the stronger cannabinoid. This applies whether you are comparing it with THCA in its raw form, where it's not psychoactive at all, or in its decarbed form when it becomes psychoactive Delta-9 THC.

We do not yet have enough information on how HHC-O and HHC-P work, but in the experience of users, these compounds are psychoactive, sedative, can relieve tension and improve sleep, or induce euphoric states. As is the case with HHC and other cannabinoids, HHC-O and HHC-P may cause side effects.

Psychoactive: Yes, THCP is the most potent compound found in cannabis. The Science-y Stuff: THCP binds to CB1 receptors in the brain and nervous system, producing powerful and euphoric effects.

THC is responsible for the psychoactive effects of street cannabis, whereas CBD is non-psychoactive. In addition to THC and CBD, our research includes the study of other cannabinoids.

“The main cannabinoid types that are usually detected in each breeding strain or cultivar of cannabis are THC, CBD, CBN, CBG and CBC. However, there can be an enormous variation in their quantitative ratios.”(3). THCV is now also considered to be a main cannabinoid.

Higher levels of THCP may also produce sedative effects similar to high doses of THC and are potentially capable of soothing insomnia or relieving intractable pain. However, there is no solid evidence on how exactly THCP affects humans or which strains might contain higher levels of the cannabinoid.

Delta-8 THC generally produces a more potent effect than delta-10 THC. While delta-8 THC is known for its milder psychoactive effects compared to delta-9 THC, delta-10 THC is often described as even less potent, with users reporting a subtler high.

Delta-9 THC is renowned for delivering a robust and intense psychoactive experience. Users commonly experience a euphoric high, altered sensory perception, and a sense of relaxation. The effects of delta-9 are often more immediate and intense compared to its milder delta-8 THC.

Both CBD and CBN are cannabinoids, or compounds derived from cannabis plants. According to Sandland Sleep, CBN is the most sedative out of all the compounds in cannabis. CBN was discovered recently from decomposed THC (the psychoactive compound in cannabis).